GDC-0326
| CAS No. | 1282514-88-8 | Cat. No. | BCP19635 |
| Name | GDC-0326 | ||
| Synonyms | |||
| Formula | C19H22N6O3 | M. Wt | 382.42 |
| Description | GDC-0326 is a potent and selective inhibitor of α-Isoform of Phosphoinositide 3-Kinase (PI3Kalpha inhibitor). GDC-0326 achieves a very high level of selectivity over other kinases. GDC-0326 has low plasma CL in human. Within the PI3 kinase family, there are four class I PI3K isoforms (α, β, δ, and γ). Of these isoforms, PI3Kα is the most commonly associated with cancers. | ||
| Pathways | PI3K/Akt/mTOR | ||
| Targets | PI3K | ||
Structure
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