Bazedoxifene acetate

CAS No.	198481-33-3	Cat. No.	BCP19656
Name	Bazedoxifene acetate
Synonyms	WAY-TES 424;WAY-140424; WAY140424; WAY 140424; TSE 424; TSE424; TSE-424; Viviant;
Formula	C30H34N2O3.C2H4O2	M. Wt	530.66

Description	Bazedoxifene, also known as WAY-140424 and TSE 424, is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis. Bazedoxifene is an indole-based ER ligand that binds to both ERα (IC50 = 26 nM) and ERβ (IC50 = 99 nM).
Pathways	Hormone Pathay
Targets	Estrogen Receptor

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