LJH 685
| CAS No. | 1627710-50-2 | Cat. No. | BCP19686 |
| Name | LJH 685 | ||
| Synonyms | LJH-685;LJH685; | ||
| Formula | C22H21F2N3O | M. Wt | 381.42 |
| Description | LJH685 efficiently inhibits RSK activity in cells. LJH685 RSK inhibition correlates with antiproliferative effects in MAPK pathway-dependent cancer cell lines only in anchorage-independent growth setting. The EC 50 values of LJH685 is 0.73 and 0.79 μM in MDA-MB-231 and H358. | ||
| Pathways | PI3K/Akt/mTOR MAPK Pathway | ||
| Targets | RSK | ||
Structure
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