LUF6000
| CAS No. | 890087-21-5 | Cat. No. | BCP25002 |
| Name | LUF6000 | ||
| Synonyms | LUF 6000; LUF-6000; | ||
| Formula | C22H20Cl2N4 | M. Wt | 411.33 |
| Description | LUF6000 is an A(3) adenosine receptor agonist. LUF6000 administration induced anti-inflammatory effect. The anti-inflammatory effect of LUF6000, mechanism of action, and the differential effects on inflammatory and normal cells position this allosteric modulator as an attractive and unique drug candidate. The A3 adenosine receptor (A3AR) is overexpressed in inflammatory cells and in the peripheral blood mononuclear cells of individuals with inflammatory conditions. Agonists to the A3AR are known to induce specific anti-inflammatory effects upon chronic treatment. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Adenosine Receptor | ||
Structure
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