Cyclic AMP

  • Chemical Properties
CAS No. 60-92-4 Cat. No. BCP19737
Name Cyclic AMP
Synonyms Adenosine 3',5'-cyclophosphate; Cyclic 3',5'-monophosphate adenosine; cAMP;
Formula C10H12N5O6P M. Wt 329.21
  • Biological Activity
Description Cyclic AMP is an adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH. cAMP is synthesized from ATP by adenylate cyclase. Adenylate cyclase is located at the cell membranes. Adenylate cyclase is activated by the hormones glucagon and adrenaline and by G protein. Liver adenylate cyclase responds more strongly to glucagon, and muscle adenylate cyclase responds more strongly to adrenaline. cAMP decomposition into AMP is catalyzed by the enzyme phosphodiesterase.
Pathways Others Pathway 
Targets Others 

Structure

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