Cyclic AMP
CAS No. | 60-92-4 | Cat. No. | BCP19737 |
Name | Cyclic AMP | ||
Synonyms | Adenosine 3',5'-cyclophosphate; Cyclic 3',5'-monophosphate adenosine; cAMP; | ||
Formula | C10H12N5O6P | M. Wt | 329.21 |
Description | Cyclic AMP is an adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH. cAMP is synthesized from ATP by adenylate cyclase. Adenylate cyclase is located at the cell membranes. Adenylate cyclase is activated by the hormones glucagon and adrenaline and by G protein. Liver adenylate cyclase responds more strongly to glucagon, and muscle adenylate cyclase responds more strongly to adrenaline. cAMP decomposition into AMP is catalyzed by the enzyme phosphodiesterase. | ||
Pathways | Others Pathway | ||
Targets | Others |
Structure
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