MK0557

  • Chemical Properties
CAS No. 328232-95-7 Cat. No. BCP19822
Name MK0557
Synonyms MK-0557;MK 0557;
Formula C22H19FN4O3 M. Wt 406.41
  • Biological Activity
Description MK-0557 is a highly selective, orally administered neuropeptide NPY5R antagonist, could limit weight regain after very-low-calorie diet (VLCD)-induced weight loss. Neuropeptide Y (NPY) is a potent orexigenic neuropeptide, and antagonism of NPY Y1 and NPY Y5 receptors (NPYxR) is considered a potentially important anti-obesity drug target.
Pathways GPCR/G Protein 
Targets Neuropeptide Receptor 

Structure

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