Branaplam
| CAS No. | 1562338-42-4 | Cat. No. | BCP19909 |
| Name | Branaplam | ||
| Synonyms | LMI-070;LMI070;LMI 070;NVS-SM1; | ||
| Formula | C22H27N5O2 | M. Wt | 393.48 |
| Description | Branaplam, also known as NVS-SM1 and LMI-070, is a highly potent, selective and orally active small molecule SMN2 splicing modulator as a potential treatment for SMA Type 1 (Spinal Muscular Atrophy) .NVS-SM1 works by increasing the amount of functional SMN protein produced by the “back-up” gene, SMN2, through modifying its splicing. | ||
| Related Products | 1562338-39-9（Branaplam hydrochloride） | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | DNA/RNA Synthesis | ||
Structure
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