A-317491

  • Chemical Properties
CAS No. 475205-49-3 Cat. No. BCP25091
Name A-317491
Synonyms A317491; A 317491;
Formula C33H27NO8 M. Wt 565.58
  • Biological Activity
Description A-317491 is a potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors. A-317491 transiently attenuates cancer-induced bone pain in mice. A-317491 reverses inflammatory mechanical hyperalgesia through action at peripheral receptors in rats. A-317491 reduces chronic inflammatory and neuropathic pain in the rat.
Pathways Ion Channel/Membrane Transporter Neuro Signaling Pathway GPCR/G Protein Others Pathway 
Targets P2 Receptor  Autophagy 

Structure

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