Lappaconitine

  • Chemical Properties
CAS No. 32854-75-4 Cat. No. BCP19975
Name Lappaconitine
Synonyms (+)-Lappaconitine;
Formula C32H44N2O8 M. Wt 584.71
  • Biological Activity
Description Lappaconitine is a cardiac Na+ channel blocker found in species of Aconitum. It displays many biological activities, including increasing pain thresholds and downregulating expression of P2X3 receptors in DRG neurons, decreasing paw and ear edema, and inducing negative inotropic activity.
Pathways Ion Channel/Membrane Transporter Neuro Signaling Pathway GPCR/G Protein 
Targets P2 Receptor  

Structure

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