LY3214996
| CAS No. | 1951483-29-6 | Cat. No. | BCP19982 |
| Name | LY3214996 | ||
| Synonyms | LY 3214996;LY-3214996; | ||
| Formula | C22H27N7O2S | M. Wt | 453.56 |
| Description | LY-3214996 is a otent and selective, orally available inhibitor of extracellular signal-regulated kinase (ERK) 1 and 2, with potential antineoplastic activity. Upon oral administration, LY3214996 inhibits both ERK 1 and 2, thereby preventing the activation of mitogen-activated protein kinase (MAPK)/ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival. | ||
| Pathways | MAPK Pathway | ||
| Targets | MEK/ERK | ||
Structure
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