SAR407899
CAS No. | 923359-38-0 | Cat. No. | BCP20035 |
Name | SAR407899 | ||
Synonyms | SAR-407899;SAR 407899; | ||
Formula | C14H16N2O2 | M. Wt | 244.29 |
Description | SAR407899 is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and rat ROCK-2, respectively. | ||
Pathways | Cell Cycle/DNA Damage TGF beta/Smad Wnt/Stem Cell | ||
Targets | ROCK |
Structure
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