SAR407899

  • Chemical Properties
CAS No. 923359-38-0 Cat. No. BCP20035
Name SAR407899
Synonyms SAR-407899;SAR 407899;
Formula C14H16N2O2 M. Wt 244.29
  • Biological Activity
Description SAR407899 is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and rat ROCK-2, respectively.
Pathways Cell Cycle/DNA Damage TGF beta/Smad  Wnt/Stem Cell 
Targets ROCK 

Structure

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