PD 166866

  • Chemical Properties
CAS No. 192705-79-6 Cat. No. BCP20054
Name PD 166866
Synonyms PD166866;PD-166866;
Formula C20H24N6O3 M. Wt 396.44
  • Biological Activity
Description PD166866 is a selective inhibitor of the FGF-1 receptor tyrosine kinase (FGFR1) with IC50 = 55 nM, and no effect on c-Src, PDGFR-b, EGFR or insulin receptor tyrosine kinases or MEK, PKC, and CDK4. PD166866 has clear antiproliferative effects.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets FGFR 

Structure

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