AZD5153 6-Hydroxy-2-naphthoic acid

  • Chemical Properties
CAS No. 1869912-40-2 Cat. No. BCP20066
Name AZD5153 6-Hydroxy-2-naphthoic acid
Synonyms AZD-5153 HNT salt;AZD 5153 6-Hydroxy-2-naphthoic acid; AZD-5153 6-Hydroxy-2-naphthoic acid;AZD-5153; AZD5153; AZD 5153;
Formula C36H41N7O6 M. Wt 667.75
  • Biological Activity
Description AZD5153 6-Hydroxy-2-naphthoic acid is the 6-Hydroxy-2-naphthoic acid of AZD5153. AZD5153 is a potent, selective, and orally available BET/BRD4 bromodomain inhibitor; disrupts BRD4 with an IC50 of 1.7 nM.
Pathways Epigenetics 
Targets Epigenetic Reader Domain 

Structure

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