ROC-325
CAS No. | 1859141-26-6 | Cat. No. | BCP20110 |
Name | ROC-325 | ||
Synonyms | ROC 325;ROC325; | ||
Formula | C28H27ClN4OS | M. Wt | 503.06 |
Description | ROC-325 is an autophagy inhibitor. ROC-325 exhibited superior in vitro anticancer effects compared with the existing autophagy inhibitor hydroxychloroquine (HCQ) in 12 different cancer cell lines with diverse genetic backgrounds. ROC-325 antagonized RCC growth and survival in an ATG5/7-dependent manner, induced apoptosis, and exhibited favorable selectivity. | ||
Pathways | Others Pathway | ||
Targets | Autophagy |
Structure
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