Protein degrader 1 hydrochloride

  • Chemical Properties
CAS No. 1448189-80-7 Cat. No. BCP25135
Name Protein degrader 1 hydrochloride
Synonyms Protein degrader 1 HCl;MDK7526 HCl;MDK 7526 HCl; MDK-7526 HCl; MDK 7526; VHL Ligand 1; ULM-1;VH032 desacetyl Hydrochloride; VH032 amine HCl;
Formula C22H31ClN4O3S M. Wt 467.02
  • Biological Activity
Description Protein degrader 1, also known as VHL Ligand 1; MDK7526, is a potent and selective protein degrader. MDK7526 is potential useful for the targeted degradation of the androgen receptor. MDK7526 binds androgen receptor such that androgen receptor is placed in proximity to the ubiquitin ligase to effect degrdn. (and inhibition) of androgen receptor.
Pathways Hormone Pathay Others Pathway 
Targets Androgen Receptor  PROTAC 

Structure

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