Avapritinib
| CAS号 | 1703793-34-3 | 货号 | BCP20175 |
| 中文名 | Avapritinib | ||
| 英文名 | Avapritinib | ||
| 中文别名 | |||
| 英文别名 | BLU-285; BLU 285; BLU285; | ||
| 分子式 | C26H27FN10 | 分子量 | 498.57 |
| 生物活性 | BLU-285, also known as Avapritinib, is a potent and selective inhibitor of PDGFRα D842V and KIT Exon 17 mutants and is being developed as a highly targeted therapy for SM, a disorder of the mast cells in which a KIT Exon 17 mutation is the primary driver of disease. BLU-285 is currently being developed by Blueprint. | ||
| 信号通路 | Angiogenesis/Protein Tyrosine Kinase | ||
| 靶 点 | c Kit | ||
结构式
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