Naluzotan

Description	Naluzotan, also known as PRX-00023, is a selective and potent 5-HT1A receptor partial agonist, for the treatment of generalized anxiety disorder and major depressive disorder. Naluzotan demonstrated significant antidepressant and anxiolytic effects as per the HAM-D and MADRS and the HAM-A, respectively, in some trials, but in others it did not. In the end it was not found to be significantly superior enough to placebo and development was stopped.
Pathways	Ion Channel/Membrane Transporter Neuro Signaling Pathway GPCR/G Protein
Targets	5 HT Receptor/Serotonin Receptor Potassium Channel

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