LDC-3140
| CAS No. | 1453833-30-1 | Cat. No. | BCP25189 |
| Name | LDC-3140 | ||
| Synonyms | LDC3140; LDC 3140; LDC043140; | ||
| Formula | C23H33N7O | M. Wt | 423.57 |
| Description | LDC3140, also known as LDC043140, is a potent CDK7 inhibitor. Cyclin-dependent kinase 7 (CDK7) activates cell cycle CDKs and is a member of the general transcription factor TFIIH. Cyclin-dependent kinase 7 controls mRNA synthesis by affecting stability of preinitiation complexes, leading to altered gene expression, cell cycle progression, and survival of tumor cells. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | CDK | ||
Structure
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