Evolocumab

Chemical Properties

CAS No.	1256937-27-5	Cat. No.	BCP25203
Name	Evolocumab
Synonyms	AMG-145;AMG 145;AMG145;
Formula	C6242H9648N1668O1996S56	M. Wt	141.8 kg/mol

Biological Activity

Description	Evolocumab is a fully human monoclonal antibody that inhibits proprotein convertase subtilisin/kexin type 9 (PCSK9). PCSK9 is a protein that targets LDL receptors for degradation and thereby reduces the liver's ability to remove LDL-C, or "bad" cholesterol, from the blood.

Description

Evolocumab is a fully human monoclonal antibody that inhibits proprotein convertase subtilisin/kexin type 9 (PCSK9). PCSK9 is a protein that targets LDL receptors for degradation and thereby reduces the liver's ability to remove LDL-C, or "bad" cholesterol, from the blood.

Structure

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