TCS-OX2-29 HCl
| CAS No. | 1610882-30-8 | Cat. No. | BCP20354 |
| Name | TCS-OX2-29 HCl | ||
| Synonyms | TCSOX229; TCSOX-229; TCSOX 229; TCS-OX229; TCS OX2 29; TCS OX229; TCS-OX2-29; TCS OX-229; | ||
| Formula | C23H31N3O3.HCl | M. Wt | 433.98 |
| Description | TCS-OX2-29 is a selective OX2 receptor antagonist (IC50 = 40 nM). Orexin, which is mainly produced by orexin-expressing neurons in the lateral hypothalamus (LH), plays an important role in pain modulation. Both kinds of orexin-1 (Ox1) and orexin-2 (Ox2) receptors have been found at high density in the ventral tegmental area (VTA) and nucleus accumbens (NAc). | ||
| Pathways | GPCR/G Protein | ||
| Targets | OX Receptor | ||
Structure
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