MK-0941 mesylate
| CAS No. | 1137916-97-2 | Cat. No. | BCP25241 |
| Name | MK-0941 mesylate | ||
| Synonyms | MK-0941; MK 0941 mesylate; MK0941 mesylate; | ||
| Formula | C21H24N4O6S.CH4O3S | M. Wt | 556.61 |
| Description | MK-0941 mesylate (MK0941) is a novel potent, orally active Glucokinase (GK) activator with EC50 of 0.240 and 0.065 uM in 2.5 and 10 mM glucose, respectively; increases insulin secretion by 17-fold and glucose uptake up to 18-fold, respectively, in isolated rat islets of Langerhans and hepatocytes at 10 uM; exhibits strong glucose-lowering activity in rodent models of type 2 diabetes and healthy dogs. | ||
| Related Products | 752240-01-0（MK-0941） | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | Glucokinase | ||
Structure
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