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CAS No. | 1001264-89-6 | Cat. No. | BCP03514 |
Name | Ipatasertib | ||
Synonyms | GDC-0068;GDC0068;GDC 0068; RG7440; RG-7440; RG 7440; | ||
SMILES | ClC1=CC=C([C@@H](CNC(C)C)C(N2CCN(C3=C([C@](C)C[C@]4O)C4=NC=N3)CC2)=O)C=C1 | ||
Chemical Name | |||
Formula | C24H32ClN5O2 | M. Wt | 458 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Ipatasertib, also known as GDC-0068, is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GDC-0068 binds to and inhibits the activity of Akt in a non-ATP-competitive manner, which may result in the inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. |
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