Irinotecan hydrochloride New
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 100286-90-6 | Cat. No. | BCP17234 |
| Name | Irinotecan hydrochloride | ||
| Synonyms | Camptothecin 11 hydrochloride;CPT11; CPT-11; CPT 11; U101440E; HSDB 7607; HSDB-7607; HSDB7607; | ||
| SMILES | CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7.Cl | ||
| Chemical Name | |||
| Formula | C33H39ClN4O6 | M. Wt | 623.14 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Irinotecan hydrochloride is the hydrochloride salt of a semisynthetic derivative of camptothecin, a cytotoxic, quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata. Irinotecan, a prodrug, is converted to a biologically active metabolite 7-ethyl-10-hydroxy-camptothecin (SN-38) by a carboxylesterase-converting enzyme. One thousand-fold more potent than its parent compound irinotecan, SN-38 inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA, resulting in DNA breaks that inhibit DNA replication and trigger apoptotic cell death. | ||
Recommend Products
More >
-
-
Irinotecan sucrosofate
Cat. No.：BCP49278
No.：1361317-83-0
Product Details -
Voreloxin Hydrochloride
Cat. No.：BCP49069
No.：175519-16-1
Product Details -
Indimitecan
Cat. No.：BCP46636
No.：915360-05-3
Product Details -
-
Bisantrene dihydrochloride
Cat. No.：BCP46265
No.：71439-68-4
Product Details -
ARN-21934
Cat. No.：BCP44949
No.：2230854-93-8
Product Details -
-
Rebeccamycin
Cat. No.：BCP41470
No.：93908-02-2
Product Details -
Chimmitecan
Cat. No.：BCP40436
No.：185425-25-6
Product Details -
-
Exatecan mesylate dihydrate
Cat. No.：BCP36302
No.：197720-53-9
Product Details -
Phenoxodiol
Cat. No.：BCP34699
No.：81267-65-4
Product Details -
-
-
LMP744 hydrochloride
Cat. No.：BCP34016
No.：308246-57-3
Product Details -
-
-
Levofloxacin hydrochloride
Cat. No.：BCP24629
No.：177325-13-2
Product Details -
Chebulanin
Cat. No.：BCP28487
No.：166833-80-3
Product Details
Tags:Irinotecan hydrochloride supplier,Irinotecan hydrochloride purchase,Irinotecan hydrochloride manufacturer,Irinotecan hydrochloride distributor,Irinotecan hydrochloride cost,Irinotecan hydrochloride buy,Irinotecan hydrochloride for sale