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RG3039 Chemical Structure

RG3039

Data Sheet For research use only. Not for human use.
Cat. No. :BCP08729CAS No. :1005504-62-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1005504-62-0 Cat. No. BCP08729
Name RG3039
Synonyms RG-3039;RG 3039;PF06687859;PF-06687859;PF06687859;
SMILES
Chemical Name
Formula C21H23Cl2N5O M. Wt 432.35
Purity 98% Storage Store at 4-8°C
Description RG3039, also known as PF-06687859, is a potent DcpS inhibitor. DcpS is a therapeutic target for spinal muscular atrophy. Spinal muscular atrophy (SMA) is caused by deletion or mutation of both copies of the SMN1 gene which produces an essential protein known as SMN. RG3039 improves motor function in SMA mice. RG3039 also showed activity to improve survival, function and motor unit pathologies in two SMA mouse models.
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