Microcystin-Lr
Data Sheet
For research use only. Not for human use.
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| CAS No. | 101043-37-2 | Cat. No. | BCP14915 |
| Name | Microcystin-Lr | ||
| Synonyms | |||
| SMILES | |||
| Chemical Name | |||
| Formula | C49H74N10O12 | M. Wt | 995.18 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Microcystins are hepatotoxic cyclic heptapeptide toxins produced by cyanobacteria.They are responsible for periodic poisonings of humans and livestock drinking fresh water where the blue-green algae are endemic. Microcystin-LR is a selective inhibitor of protein phosphatase 2A (PP2A) (IC50= 0.04 nM) and will completely inhibit this enzyme without affecting PP1 when used at a concentration of 0.5 nM. The PP1 IC50 is about 1.7 nM. Microcystins are at least 10 times more potent as serine/threonine PP inhibitors than okadaic acid, another microalgal toxin also used for this purpose. | ||
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