Home   >  
Cell Cycle/DNA Damage
  • Apoptosis Pathway
  • Epigenetics
∨
  >  
Sirtuin
  • HDAC
  • p53
∨
  >   Tenovin-6
Tenovin-6 Chemical Structure

Tenovin-6

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP08547CAS No. ：1011557-82-6Purity：98%
chem_1Get Quotation Now
 Tel: 0086-17754423994   or   orders@biochempartner.com
Real-Time Inquiry ×

* Required Fields.

Please complete the form below and you will get the price list in 1 minute.

Product name

  

* Applicant name

Catalog Number

  

* Institution/Company

* Email address

  

Phone number

Country

  

* Quantity Required

Remarks
Submit
Inquiry Online ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

  

* Applicant name

Catalog Number

  

* Institution/Company

* Email address

  

Phone number

Country

  

* Quantity Required

Remarks
Submit
Bulk Inquiry ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

  

* Applicant name

Catalog Number

  

* Institution/Company

* Email address

  

Phone number

Country

  

* Quantity Required

Remarks
Submit
  • Chemical Properties&Biological Activity
CAS No. 1011557-82-6 Cat. No. BCP08547
Name Tenovin-6
Synonyms Tenovin6 ;Tenovin 6;Tnv-6; Tnv6;Tnv 6;
SMILES O=C(NC(NC1=CC=C(NC(CCCCN(C)C)=O)C=C1)=S)C2=CC=C(C(C)(C)C)C=C2
Chemical Name
Formula C25H34N4O2S M. Wt 454.6
Purity 98% Storage Store at 4-8°C
Description Tenovin-6, also known as Tnv-6, is a bioactive small molecule SIRT2 inhibitor with anti-neoplastic activity. Inhibition of the Sirtuin class of protein deacetylases with activation of p53 function is associated with the pro-apoptotic effects of Tnv-6 in many tumors. Tnv-6 causes non-genotoxic cytotoxicity, without adversely affecting human clonogenic hematopoietic progenitors in vitro, or murine hematopoiesis. Mechanistically, exposure of CLL cells to Tnv-6 did not induce cellular apoptosis or p53-pathway activity. Transcriptomic profiling identified a gene program influenced by Tnv-6 that included autophagy-lysosomal pathway genes.
  • Quality Control&Technical Support
LCMS H-NMR
In the process of purchasing and using Biochempartner products, you can consult us if you have any problems: orders@biochempartner.com. We will try our best to solve all your doubts.

Recommend Products

More >

Tags:Tenovin-6 supplier,Tenovin-6 purchase,Tenovin-6 manufacturer,Tenovin-6 distributor,Tenovin-6 cost,Tenovin-6 buy,Tenovin-6 for sale

0086-13720134139