VTP-27999 2,2,2-trifluoroacetate
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1013937-63-7 | Cat. No. | BCP27647 |
| Name | VTP-27999 2,2,2-trifluoroacetate | ||
| Synonyms | VTP-27999 TFA; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C26H41ClN4O5.C2HF3O2 | M. Wt | 639.1 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | VTP-27999 is a highly potent and selective renin inhibitor (IC50 = 0.47 nM). VTP-27999 demonstrated excellent selectivity over related and unrelated off-targets, >15% oral bioavailability in three species, oral efficacy in a double transgenic rat model of hypertension, and good exposure in humans. | ||
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