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Alisertib Chemical Structure

Alisertib

Data Sheet For research use only. Not for human use.
Cat. No. :BCP01823CAS No. :1028486-01-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1028486-01-2 Cat. No. BCP01823
Name Alisertib
Synonyms MLN 8237;MLN8237;MLN-8237;
SMILES
Chemical Name
Formula C27H20ClFN4O4 M. Wt 518.94
Purity 98% Storage Store at 4-8°C
Description Alisertib, also known as MLN8237, is a second-generation, orally bioavailable, highly selective small molecule inhibitor of the serine/threonine protein kinase Aurora A kinase with potential antineoplastic activity. Aurora kinase inhibitor MLN8237 binds to and inhibits Aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation.
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