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Daptomycin Chemical Structure

Daptomycin

Data Sheet For research use only. Not for human use.
Cat. No. :BCP05708CAS No. :103060-53-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 103060-53-3 Cat. No. BCP05708
Name Daptomycin
Synonyms LY 146032; LY-146032; LY146032;Cidecin; Cubicin;
SMILES O=C1NCC(N[C@@H](CCCN)C(N[C@@H](CC(O)=O)C(N[C@H](C)C(N[C@@H](CC(O)=O)C(NCC(N[C@H](CO)C(N[C@@H]([C@H](C)CC(O)=O)C(N[C@@H](CC(C2=CC=CC=C2N)=O)C(OC(C)C1NC([C@@H](NC([C@@H](NC([C@@H](NC(CCCCCCCCC)=O)CC3=CN
Chemical Name
Formula C72H101N17O26 M. Wt 1620.68
Purity 98% Storage Store at 4-8°C
Description Daptomycin is a novel lipopeptide antibiotic used in the treatment of certain infections caused by Gram-positive organisms. It is a naturally-occurring compound found in the soil saprotroph Streptomyces roseosporus. Its distinct mechanism of action means that it may be useful in treating infections due to Staphylococcus aureus. The efficacies of low- versus high-dose vancomycin (10 versus 110 mg/kg), daptomycin (1 versus 10 mg/kg), and tigecycline (1 versus 10 mg/kg) intravenous prophylaxis were compared using in vivo bioluminescence imaging, ex vivo bacterial counts, and biofilm formation. High-dose vancomycin, daptomycin, and tigecycline resulted in similar reductions in bacterial burden and biofilm formation.
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