Salidroside

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP04178CAS No. ：10338-51-9Purity：98%

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CAS No.	10338-51-9	Cat. No.	BCP04178
Name	Salidroside
Synonyms
SMILES
Chemical Name
Formula	C14H20O7	M. Wt	300.3
Purity	98%	Storage	Store at 4-8°C
Description	Salidroside inhibits the growth of various human cancer cell lines in concentration- and time-dependent manners, and the sensitivity to salidroside is different in those cancer cell lines. Salidroside could cause G1-phase or G2-phase arrest in different cancer cell lines, meanwhile, salidroside resultes in a decrease of CDK4, cyclin D1, cyclin B1 and Cdc2, and upregulates the levels of p27(Kip1) and p21(Cip1). Salidroside also alleviates cell viability loss and apoptotic cell death induced by H(2)O(2) stimulation in cultured NGF-differentiated PC12 cells by activating ERK1/2 pathway and inhibiting caspase-3 activation.Salidroside activates the PI3K/Akt pathway resulting in protective effects against MPP(+)-induced apoptosis in PC12 cells, which may be used in the treatment of Parkinson's disease (PD).