Sumatriptan
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CAS No. | 103628-46-2 | Cat. No. | BCP02237 |
Name | Sumatriptan | ||
Synonyms | Gr-43175;Gr 43175;Gr43175; | ||
SMILES | |||
Chemical Name | |||
Formula | C14H21N3O2S | M. Wt | 295.4 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Sumatriptan is structurally similar to serotonin (5-HT), and is a 5-HT receptor (types 5-HT1D and 5-HT1B[7]) agonist. Sumatriptan's primary therapeutic effect, however, is in its inhibition of the release of Calcitonin gene-related peptide (CGRP), likely through its 5-HT1D/1B receptor-agonist action.This is substantiated by the efficacy of newly developed CGRP antagonists and antibodies in the preventative treatment of migraine. |
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