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AG17 Chemical Structure

AG17

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP06486CAS No. ：10537-47-0Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 10537-47-0 Cat. No. BCP06486
Name AG17
Synonyms AG 17; Malonoben; NSC 242557; RG 50872; SF 6847; Tyrphostin 9; Tyrphostin A 9; Tyrphostin AG 17;
SMILES
Chemical Name
Formula C18H22N2O M. Wt 282.38
Purity 98% Storage Store at 4-8°C
Description Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of protein tyrosine kinases. Tyrphostins are a class of antiproliferative compounds which act as protein tryrosine kinase blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor (EGF) receptor kinase block EGF-dependent cell proliferation.1 AG-17 is an inhibitor of EGF receptor kinase with an IC50 value of 460 μM in the human epidermoid carcinoma cell line A431
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