Risedronic acid New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 105462-24-6 | Cat. No. | BCP13805 |
| Name | Risedronic acid | ||
| Synonyms | NE-58095; NE 58095; NE58095;Risedronate; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C7H11NO7P2 | M. Wt | 283.11 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Risedronate, which was promoted in Croatia a few months ago, is the latest (III) generation of bisphosphonates, the most efficient anti-resorption drugs that inhibit osteoclast-mediated bone resorption and change the bone metabolism. Risedronate is hence the first line of bisphosphonates for the reduction of vertebral and non-vertebral fracture risks in postmenopausal women with osteoporosis or those with a high risk of osteoporosis. It also efficiently prevents bone loss or improves bone density in men and women on a long-term corticosteroid therapy . The administration of 20 and 25 mg/kg risedronate for 4 days led to decreases of parasitemia of 68.9% and 83.6%, respectively. On the seventh day of treatment the inhibitions were 63% and 88.9% with 20 and 25 mg/kg, respectively. After recovering the parasitemia, a dose-response curve was obtained for estimating the ID50 (dose causing 50% inhibition), equivalent to 17 ± 1.8 mg/kg after 7 days of treatment. | ||
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