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WAY-600 Chemical Structure

WAY-600

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP02897CAS No. ：1062159-35-6Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1062159-35-6 Cat. No. BCP02897
Name WAY-600
Synonyms WAY 600;WAY600;
SMILES
Chemical Name
Formula C28H30N8O M. Wt 494.59
Purity 98% Storage Store at 4-8°C
Description Immune-complex kinase assay shows mTORC2-specific substrate His6-AKT or the mTORC1 substrate His6-S6K is dose dependently inhibited by WAY-600. WAY-600 globally inhibits mTOR signaling and AKT function in cellular models dose dependently. WAY-600 profoundly inhibits cap-dependent and global protein synthesis in MDA361, human breast cancer cells. WAY-600 shows antiproliferative effects in various cancer cell lines involving G1 cell cycle arrest and selective apoptosis. WAY-600 down-regulate angiogenic factors, VEGF and HIF-1α, in U87MG, MDA361 and LNCap cells.
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