Sodium valproate
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 1069-66-5 | Cat. No. | BCP02888 |
| Name | Sodium valproate | ||
| Synonyms | Depakene;Valrelease;Valproic acid sodium salt;Sodium valproate; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C8H15NaO2 | M. Wt | 166.19 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | in vitro: Valproic acid had the effect on the growth and death of HeLa cervical cancer cells in relation to reactive oxygen species (ROS) and glutathione (GSH). Dose- and time-dependent growth inhibition was observed in HeLa cells with an IC50 of approximately 10 mM at 24 h. DNA flow cytometric analysis indicated that 10 mM VPA induced a G2/M phase arrest of the cell cycle. This agent also induced apoptosis, which was accompanied by the cleavage of PARP, the activation of caspase-3, -8 and -9, and the loss of mitochondrial membrane potential (MMP; ?Ψm). All the tested caspase inhibitors significantly prevented HeLa apoptotic cell death induced by VPA, whereas TNF-α intensified the apoptotic cell death [1]. Valproic acid downregulated HDAC, increased histone H3 acetylation and enhanced the accumulation of hyperacetylated histone H3 on the VEGF promoters. in vivo: Pregnant Long Evans rats were injected with 350mg/kg VPA or saline on gestational day 13. A modified social interaction test | ||
Recommend Products
More >
-
-
Snail/HDAC-IN-1
Cat. No.：BCP48514
No.：2415281-52-4
Product Details -
-
-
Quisinostat HCl
Cat. No.：BCP44306
No.：1083078-98-1
Product Details -
-
Pracinostat Dihydrochloride
Cat. No.：BCP43352
No.：929016-98-8
Product Details -
-
Resminostat hydrochloride
Cat. No.：BCP39644
No.：1187075-34-8
Product Details -
SKLB-23bb
Cat. No.：BCP37616
No.：1815580-06-3
Product Details -
-
-
Sodium Butyrate
Cat. No.：BCP31813
No.：156-54-7
Product Details -
-
Remetinostat
Cat. No.：BCP30561
No.：946150-57-8
Product Details -
-
-
-
-
Belinostat
Cat. No.：BCP24610
No.：866323-14-0
Product Details
Tags:Sodium valproate supplier,Sodium valproate purchase,Sodium valproate manufacturer,Sodium valproate distributor,Sodium valproate cost,Sodium valproate buy,Sodium valproate for sale