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CAS No. | 108147-54-2 | Cat. No. | BCP15236 |
Name | Migalasta | ||
Synonyms | AT1001; AT 1001; AT-1001; GR181413A; GR 181413A; GR-181413A; 1-deoxygalactonojirimycin; | ||
SMILES | C1C(C(C(C(N1)CO)O)O)O | ||
Chemical Name | |||
Formula | C6H13NO4 | M. Wt | 163.17 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Migalastat is a potent, orally available inhibitor of α-GalA (IC50: 4 μM).[4] When binding to faulty α-GalA, it shifts the folding behaviour towards the proper conformation, resulting in a functional enzyme provided the mutation is amenable.Molecules with this type of mechanism are called pharmacological chaperones. |
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