LY-2510924
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CAS No. | 1088715-84-7 | Cat. No. | BCP20800 |
Name | LY-2510924 | ||
Synonyms | LY2510924 ; LY 2510924; | ||
SMILES | O=C(NCC(N[C@](CCC(N[C@]1CC2=CC=CC=C2)=O)C(N[C@](C(N)=O)CCCCNC(C)C)=O)=O)[C@@H](NC([C@@](NC([C@@H](NC([C@](NC1=O)CC3=CC=C(O)C=C3)=O)CCCCNC(C)C)=O)([H])CCCNC(N)=N)=O)CC4=CC(C=CC=C5)=C5C=C4 | ||
Chemical Name | |||
Formula | C62H87N13O11 | M. Wt | 1190.46 |
Purity | 98% | Storage | Store at 4-8°C |
Description | LY2510924 is an inhibitor of CXC chemokine receptor 4 (CXCR4), with potential antineoplastic activity. Upon subcutaneous administration, CXCR4 inhibitor LY2510924 binds to the chemokine receptor CXCR4, thereby preventing CXCR4 binding to its ligand, stromal derived factor-1 (SDF-1), and subsequent receptor activation. This may result in decreased tumor cell proliferation and migration. CXCR4, a chemokine receptor belonging to the G protein-coupled receptor (GPCR) gene family, plays an important role in chemotaxis and angiogenesis and is upregulated in several tumor cell types. |
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