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LY-2510924 Chemical Structure

LY-2510924

Data Sheet For research use only. Not for human use.
Cat. No. :BCP20800CAS No. :1088715-84-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1088715-84-7 Cat. No. BCP20800
Name LY-2510924
Synonyms LY2510924 ; LY 2510924;
SMILES O=C(NCC(N[C@](CCC(N[C@]1CC2=CC=CC=C2)=O)C(N[C@](C(N)=O)CCCCNC(C)C)=O)=O)[C@@H](NC([C@@](NC([C@@H](NC([C@](NC1=O)CC3=CC=C(O)C=C3)=O)CCCCNC(C)C)=O)([H])CCCNC(N)=N)=O)CC4=CC(C=CC=C5)=C5C=C4
Chemical Name
Formula C62H87N13O11 M. Wt 1190.46
Purity 98% Storage Store at 4-8°C
Description LY2510924 is an inhibitor of CXC chemokine receptor 4 (CXCR4), with potential antineoplastic activity. Upon subcutaneous administration, CXCR4 inhibitor LY2510924 binds to the chemokine receptor CXCR4, thereby preventing CXCR4 binding to its ligand, stromal derived factor-1 (SDF-1), and subsequent receptor activation. This may result in decreased tumor cell proliferation and migration. CXCR4, a chemokine receptor belonging to the G protein-coupled receptor (GPCR) gene family, plays an important role in chemotaxis and angiogenesis and is upregulated in several tumor cell types.
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