CI994
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CAS No. | 112522-64-2 | Cat. No. | BCP02577 |
Name | CI994 | ||
Synonyms | Acetyldinaline;Tacedinaline;PD 123654;Goe 5549;CI 994;CI994; | ||
SMILES | |||
Chemical Name | |||
Formula | C15H15N3O2 | M. Wt | 269.3 |
Purity | 98% | Storage | Store at 4-8°C |
Description | CI-994 (< 160 mM) shows cytostatic effect with concomitant increase at G0/G1 phase, a reduction at S phase level and increased apoptosis in A-549 and LX-1 cells. CI-994 inhibits growth of LNCaP cell with IC50 of 7.4 μM.CI-994 exerts activity against several tumor cell lines with greater cytotoxicity against the solid tumors relative to both the leukemia and normal fibroblast cell lines. CI-994 inhibits growth of rat leukemia BCLO cells with IC50 of 2.5 μM. |
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