Mosapride

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP06695CAS No. ：112885-41-3Purity：98%

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CAS No.	112885-41-3	Cat. No.	BCP06695
Name	Mosapride
Synonyms	Moza;TAK-370;TAK 370;TAK370;AS-4370;AS4370;AS 4370;Gasmotin;
SMILES
Chemical Name
Formula	C21H25ClFN3O3	M. Wt	421.89
Purity	98%	Storage	Store at 4-8°C
Description	Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist. The major active metabolite of mosapride, known as M1, additionally acts as a 5HT3 antagonist, which accelerates gastric emptying throughout the whole of the gastrointestinal tract in humans, and is used for the treatment of gastritis, gastro-oesophageal reflux disease, functional dyspepsia and irritable bowel syndrome. It is recommended to be taken on an empty stomach (i.e. at least one hour before food or two hours after food). In addition to its prokinetic properties, mosapride also exerts anti-inflammatory effects on the gastrointestinal tract which may contribute to some of its therapeutic effects. Mosapride also promotes neurogenesis in the gastrointestinal tract which may prove useful in certain bowel disorders. The neurogenesis is due to mosapride's effect on the 5-HT4 receptor where it acts as an agonist.Its common side effects include dry mouth, abdominal pain, dizziness, headache, insomnia, malaise,