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GDC0834
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CAS No. | 1133432-49-1 | Cat. No. | BCP08433 |
Name | GDC0834 | ||
Synonyms | GDC-0837;GDC 0837; | ||
SMILES | |||
Chemical Name | |||
Formula | C33H36N6O3S | M. Wt | 596.74 |
Purity | 98% | Storage | Store at 4-8°C |
Description | GDC-0834 is a small molecule inhibitor of Btk potentially useful in the treatment of RA and lymphoid malignancies. Administration of GDC-0834 (30 -- 100 mg/kg) in a rat CIA model induced a decrease of ankle swelling and reduction of morphologic pathology in a dose-dependent manner. |
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