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Idelalisib Chemical Structure

Idelalisib

Data Sheet For research use only. Not for human use.
Cat. No. :BCP08088CAS No. :1146702-54-6Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1146702-54-6 Cat. No. BCP08088
Name Idelalisib
Synonyms CAL101, GS-1101; GS 1101; GS1101; CAL-101; CAL 101;
SMILES
Chemical Name
Formula C21H16FN7O M. Wt 401.41
Purity 98% Storage Store at 4-8°C
Description Idelalisib, also known as CAL-101, is a PI3K-delta inhibitor with potential immunomodulating and antineoplastic activities. CAL-101 inhibits the production of the second messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3), preventing the activation of the PI3K signaling pathway and thus inhibiting tumor cell proliferation, motility, and survival. Unlike other isoforms of PI3K, PI3K-delta is expressed primarily in hematopoietic lineages. The targeted inhibition of PI3K-delta is designed to
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