Idelalisib
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CAS No. | 1146702-54-6 | Cat. No. | BCP08088 |
Name | Idelalisib | ||
Synonyms | CAL101, GS-1101; GS 1101; GS1101; CAL-101; CAL 101; | ||
SMILES | |||
Chemical Name | |||
Formula | C21H16FN7O | M. Wt | 401.41 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Idelalisib, also known as CAL-101, is a PI3K-delta inhibitor with potential immunomodulating and antineoplastic activities. CAL-101 inhibits the production of the second messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3), preventing the activation of the PI3K signaling pathway and thus inhibiting tumor cell proliferation, motility, and survival. Unlike other isoforms of PI3K, PI3K-delta is expressed primarily in hematopoietic lineages. The targeted inhibition of PI3K-delta is designed to |
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