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Basmisanil Chemical Structure

Basmisanil

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP19013CAS No. ：1159600-41-5Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1159600-41-5 Cat. No. BCP19013
Name Basmisanil
Synonyms RG1662; RO5186582;RG-1662; RO-5186582;RG 1662; RO 5186582;
SMILES
Chemical Name
Formula C21H20FN3O5S M. Wt 445.46
Purity 98% Storage Store at 4-8°C
Description Basmisanil, also known as RG1662, RO5186582, is a highly selective inverse agonist/negative allosteric modulator of α5 subunit-containing GABAA receptors which is under development by Roche for the treatment of cognitive impairment associated with Down syndrome. As of August 2015, it is in phase II clinical trials for this indication. Down syndrome (DS) is the most commonly identifiable genetic form of intellectual disability. Individuals with DS have considerable deficits in intellectual functioning (i.e., low intellectual quotient, delayed learning and/or impaired language development) and adaptive behavior.
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