IDE 1
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CAS No. | 1160927-48-9 | Cat. No. | BCP20824 |
Name | IDE 1 | ||
Synonyms | IDE1; IDE-1; | ||
SMILES | C1=CC=C(C(=C1)C=NNC(=O)CCCCCC(=O)O)C(=O)O | ||
Chemical Name | |||
Formula | C15H18N2O5 | M. Wt | 306.31 |
Purity | 98% | Storage | Store at 4-8°C |
Description | IDE1 is a potent cell-permeable definitive endoderm formation inducer (EC50 = 125 nM, ESC) similar to IDE 2. IDE1 induces Sox17 expression. It also activates TGF-β signaling and downstream Smad2 phosphorylation. IDE1 upregulates Nodal expression. |
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