Ramatroban New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 116649-85-5 | Cat. No. | BCP05553 |
| Name | Ramatroban | ||
| Synonyms | Bay u 3406; Bay u-3405; BAY u3405; | ||
| SMILES | C1CC2=C(CC1NS(=O)(=O)C3=CC=C(C=C3)F)C4=CC=CC=C4N2CCC(=O)O | ||
| Chemical Name | |||
| Formula | C21H21FN2O4S | M. Wt | 416.47 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Ramatroban is used for the treatment of allergic rhinitis as an antagonist of the thromboxane receptor. It is also an antagonist of the DP2 receptor with IC50 values of 100-170 nM. It is more potent at the DP2 receptor than the TP receptor by 4-5 fold. It is therefore a useful tool for the elucidation of PGD2/DP2 function in eosinophils, basophils, and other cells of the TH2 cell-type. | ||
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