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GDC-0623 Chemical Structure

GDC-0623

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP28689CAS No. ：1168091-68-6Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1168091-68-6 Cat. No. BCP28689
Name GDC-0623
Synonyms GDC0623;GDC 0623;
SMILES
Chemical Name
Formula C16H14FIN4O3 M. Wt 456.21
Purity 98% Storage Store at 4-8°C
Description GDC-0623 is a potent, ATP-uncompetitive inhibitor of MEK1 (Ki=0.13 nM, +ATP), and displays 6-fold weaker potency against HCT116 (KRAS (G13D), EC50=42 nM) versus A375 (BRAFV600E, EC50=7 nM).
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