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Etoposide phosphate Chemical Structure

Etoposide phosphate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP07045CAS No. :117091-64-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 117091-64-2 Cat. No. BCP07045
Name Etoposide phosphate
Synonyms Etopofos;BMY 40481;
SMILES
Chemical Name
Formula C29H33O16P M. Wt 668.54
Purity 98% Storage Store at 4-8°C
Description Etoposide Phosphate is a derivative of Etoposide (VP-16). Etoposide is a topoisomerase II inhibitor that is widely used as an apoptosis inducer. Etoposide exhibits antineoplastic and anti-mitotic properties. Inhibits DNA synthesis and induces double-strand and single-strand DNA breaks. Cell-cycle dependent and cell-cycle specific to late S and G2 phases. Activates p53 resulting in upregulated expression of TRAIL-R2 (DR5) and Bak to overcome TRAIL resistance in Bax-deficient human colon carcinoma
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