Relebactam New
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CAS No. | 1174018-99-5 | Cat. No. | BCP17037 |
Name | Relebactam | ||
Synonyms | MK-7655; MK 7655; MK7655; | ||
SMILES | C1CC(N2CC1N(C2=O)OS(=O)(=O)O)C(=O)NC3CCNCC3 | ||
Chemical Name | |||
Formula | C12H20N4O6S | M. Wt | 348.38 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Relebactam, also known as MK-7655, a potent and selective β-lactamase inhibitor. At a concentration of 4 mg/L, MK-7655 reduced imipenem MICs for Enterobacteriaceae with KPC carbapenemases from 16-64 mg/L to 0.12-1 mg/L. MK-7655 potentiated imipenem against Enterobacteriaceae with KPC carbapenemases or combinations of β-lactamase and impermeability, but not those with metallo-carbapenemases. It augmented the activity of imipenem against P. aeruginosa in general and OprD mutants in particular. |
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