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Relebactam Chemical Structure

Relebactam

Data Sheet For research use only. Not for human use.
Cat. No. :BCP17037CAS No. :1174018-99-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1174018-99-5 Cat. No. BCP17037
Name Relebactam
Synonyms MK-7655; MK 7655; MK7655;
SMILES C1CC(N2CC1N(C2=O)OS(=O)(=O)O)C(=O)NC3CCNCC3
Chemical Name
Formula C12H20N4O6S M. Wt 348.38
Purity 98% Storage Store at 4-8°C
Description Relebactam, also known as MK-7655, a potent and selective β-lactamase inhibitor. At a concentration of 4 mg/L, MK-7655 reduced imipenem MICs for Enterobacteriaceae with KPC carbapenemases from 16-64 mg/L to 0.12-1 mg/L. MK-7655 potentiated imipenem against Enterobacteriaceae with KPC carbapenemases or combinations of β-lactamase and impermeability, but not those with metallo-carbapenemases. It augmented the activity of imipenem against P. aeruginosa in general and OprD mutants in particular.
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