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AG18 Chemical Structure

AG18

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP06838CAS No. ：118409-57-7Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 118409-57-7 Cat. No. BCP06838
Name AG18
Synonyms AG-18; AG 18; AG18; RG-50810; RG-50858; TX 825; Tyrphostin 23; Tyrphostin A23; Tyrphostin AG-18;
SMILES
Chemical Name
Formula C10H6N2O2 M. Wt 186.17
Purity 98% Storage Store at 4-8°C
Description AG-18, also known as RG-50810; RG-50858; TX 825; Tyrphostin A23; Tyrphostin AG-18. AG-18 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 35 µM in the human epidermoid carcinoma cell line A431. AG-18 inhibits internalization of the transferrin receptor by perturbing the interaction between tyrosine motifs and the medium chain subunit of the AP-2 adaptor complex.
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