Trametinib DMSO solvate
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1187431-43-1 | Cat. No. | BCP06093 |
| Name | Trametinib DMSO solvate | ||
| Synonyms | GSK-1120212 DMSO solvate;GSK1120212;GSK-1120212;GSK1120212;Trametinib;JTP-74057;JTP 74057;JTP74057; | ||
| SMILES | CN1C(C(C)=C(N(C(N(C2=O)C3CC3)=O)C4=CC=CC(NC(C)=O)=C4)C2=C1NC5=CC=C(C=C5F)I)=O.CS(C)=O | ||
| Chemical Name | |||
| Formula | C28H29FIN5O5S | M. Wt | 693.53 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Trametinib DMSO solvate is a solvated form of trametinib at 1:1 molar ratio of trametinib to dimethyl sulfoxide. Trametinib, also known as GSK1120212, GSK212 or JTP74057, is an approved and new targeted drug for the treatment of melanoma. It is a powerful and selective MEK1/MEK2 inhibitor which can effectively prevent cancer cell proliferating and can induce cell apoptosis, and increase the life of patients. | ||
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