MK-8617
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CAS No. | 1187990-87-9 | Cat. No. | BCP25371 |
Name | MK-8617 | ||
Synonyms | MK 8617;MK8617; | ||
SMILES | |||
Chemical Name | |||
Formula | C24H21N5O4 | M. Wt | 443.46 |
Purity | 98% | Storage | Store at 4-8°C |
Description | MK-8617 is a potent, selective, orally bioavailabl Pan-Inhibitor of Hypoxia-Inducible Factor Prolyl Hydroxylase 1−3 (HIF PHD1−3) for the Treatment of Anemia (PHD2 IC50 = 1.0 nM; 10-19 hr dog and moneky t1/2). Anemia is a condition of insufficient red blood cells (RBCs) or hemoglobin (Hb) levels that result in reduced functional capability, fatigue, and shortness of breath. |
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